| Title | Two new limonoids from the roots of Trichilia connaroides with inhibitory activity against nitric oxide production in lipopolysaccharide-stimulated RAW 264.7 cells |
| Author | Ji, Kai-Long |
| Publication | PHYTOCHEMISTRY LETTERS |
| Year | 2015 |
| Volume | 14 |
| Corresponding Author | Zhang, P |
| Abstract | Two new rearranged limonoids, trichiliton I (1) and 12-deacetoxyltrijugin A (2) along with four previously reported compounds (3-6) were isolated from the roots of Trichilia connaroides. Their structures were established on the basis of extensive spectroscopic analysis including HR-ESI-MS and 1D and 2D NMR. The new compounds 1 and 2 exhibited weak inhibitory effects on lipopolysaccharide-stimulated nitric oxide production in RAW 264.7 cells in a dose-dependent manner. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. |
