| Title | A new triterpenoid bearing octacosanoate from the stems and roots of Clerodendrum philippinum var. simplex (Verbenaceae) |
| Author | Yue, Jia-Rui |
| Publication | NATURAL PRODUCT RESEARCH |
| Year | 2015 |
| Volume | 29 |
| Issue | 13 |
| Corresponding Author | Xu, YK |
| Abstract | A new triterpenoid bearing octacosanoate, named taraxer-3 beta-yl octacosanoate (1), together with 13 known compounds (2-14), was isolated from the ethanol extract of the stems and roots of Clerodendrum philippinum var. simplex. The structure of taraxer-3 beta-yl octacosanoate (1) was elucidated by extensive spectroscopic analysis. Uncinatone (8) and clerodenone A (10) exhibited inhibition of lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages with IC50 values of 12.50 and 3.18 mu M, respectively. |
