About
RESEARCH INTEREST
Natural Medicinal Chemistry (including bioactive natural products finding, structure modification, total synthesis)
Pharmacology (including anti-obesity, anti- acute liver injury, anti-ulcerative colitis, etc.)
EDUCATION AND TRAINING
2011.09-2016.06 M.S./Ph.D. in Plant Science, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Science
2007.09-2011.06 B.S. in Biology, Yunnan University, Kunming, China
WORK EXPERIENCE
2024.05-Present Associate Researcher, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Science, Kunming, China
2020.02-2024.04 Assistant Researcher, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Science, Kunming, China
2019.03-2020.01 Assistant Researcher, Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai, China
2016.08-2019.02 Postdoctoral Scholar, Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai, China
HONORS AND AWARDS
2016 Zhu Li Yue Hua Outstanding Doctoral Scholarship of Chinese Academy of Sciences
Articles
(1) Kai-Long Ji, Yao-Yue Fan, Qi Gong, Qun-Fang Liu, Ming-Jun Cui, Kai-Cong Fu, Hai-Yan Zhang*, Jian-Min Yue*. Densely Functionalized Macrocyclic Sesquiterpene Pyridine Alkaloids from Maytenus austroyunnanensis. Journal of Natural Products, 2023, 86, 2315-2325. (First author)
(2) Kai-Long Ji#, Wei, Liu#, Wei-Hang Yin#, Xiang-Rong Kong, Hong-Hong Xu, Zeng-Wei Lai*, Jing-Ya Li*, Jian-Min Yue*. A new class of potent liver injury protective compounds: structural elucidation, total synthesis and bioactivity study. Acta Pharmaceutica Sinica B, 2023, 13, 3414-3424. (Co-first author)
(3) Kai-Long Ji#,*, Yan-Qing Tang#, Zheng-Yang Guo#, Pian-Chou Gongpan, Peng Sun, Jian-Mei Lu, Meng-Yuan Dai, Ting Li*. Natural geranylated sulphur-containing amides with inhibitory effect on Th17 differentiation. Chemistry & Biodiversity, 2023, 20, e202300373. (Co-first author/Co-corresponding author)
(4) Kai-Long Ji#,*, Meng-Zhen Wu#, Chao-Ying Huang, Pian-Chou Gongpan, Peng Sun, Yi-Li Sun*, Jia Li, Chun-Fen Xiao, You-Kai Xu, Qing-Fei Fan, Hua-Bin Hu, Qi-Shi Song*. Alpinia hainanensis rhizome extract ameliorates dextran sulfate sodium-induced ulcerative colitis: active ingredient investigation and evaluation. Journal of Agricultural and Food Chemistry, 2022, 70, 3989-3999. (Co-first author/Co-corresponding author)
(5) Kai-Long, Ji#, Wei, Liu#, Wei-Hang Yin, Jing-Ya Li*, Jian-Min Yue*. Quinoline alkaloids with anti-inflammatory activity from Zanthoxylum avicennae. Organic & Biomolecular Chemistry, 2022, 20, 4176-4182. (Co-first author)
(6) Meng-Zhen Wu#, Pian-Chou Gongpan#, Meng-Yuan Dai, Peng Sun, Tian-Ping Huang, You-Kai Xu, Chun-Fen Xiao, Jia Li, Yi-Li Sun*, Kai-Long Ji*. Tetrahedron, 2022, 120, 132901. (Co-corresponding author)
(7) Lan Zhou, Pian-Chou Gongpan, Qing-Fei Fan, Zhi Na, Feng-Mei Huang, Kai-Long Ji*, Qi-Shi Song*. Two new monoterpenoid indole alkaloids from Mappianthus iodoides stems. Natural Product Research, 2022, 36, 5235-5240. (Co-corresponding author)
(8) Jin-Feng Li#, Kai-Long Ji#, Peng Sun, Qiang Cai, Xiao-Ling Zheng, Yi-Dian Xiao, Dong-Hua Cao, Chun-Fen Xiao, Zong-Yi Zhang, Xiao-Nian Li, Hua-Bin Hu, Zhi-Yong Yu*, You-Kai Xu*. Structurally diverse steroids with nitric oxide inhibitory activities from Aglaia lawii leaves. Phytochemistry, 2021, 183, 112651. (Co-first author)
(9) Kai-Long Ji, Yao-Yue Fan, Hio-Ha Kuok, Qun-Fang Liu, Ting Li, Jian-Min Yue*. Macrocyclic nonapeptides incorporating uncharacterized amino acids with inhibitory effects on Th17 differentiation. CCS Chemistry, 2021, 3, 175-189. (First author)
(10) Kai-long Ji#,*, Meng-Yuan Dai#, Chun-Fen Xiao, You-Kai Xu*. Two new steroids with NO inhibitory effects from lansium domesticum. Natural Product Research, 2021, 35, 1147-1152. (Co-first author/Co-corresponding author)
(11) Kai-Long Ji, Yao-Yue Fan, Zhan-Peng Ge, Li Sheng, You-Kai Xu, Li-She Gan, Jing-Ya Li, Jian-Min Yue*. Maximumins A？D, rearranged labdane-type diterpenoids with four different carbon skeletons from Amomum maximum. Journal of Organic Chemistry, 2019, 84, 282-288. (First author)
(12) Kai-long Ji#, Xiao-Qing Gan#, You-Kai Xu, Xiu-Fen Li, Juan Guo, Mahmoud M. Dahab, Ping Zhang*. Protective effect of the essential oil of Zanthoxylum myriacanthum var. pubescens against dextran sulfate sodium-induced intestinal inflammation in mice. Phytomedicine, 2016, 23, 883-90. (Co-first author)
(13) Kai-long Ji, Xiao-Nian Li, Shang-Gao Liao, Hua-Bin Hu, Ren Li, You-Kai Xu*. Cytotoxic limonoids from the leaves of Walsura robusta. Phytochemistry Letters, 2016, 14, 234-238. (First author)
(14) Kai-long Ji, Dong-Hua Cao, Xiu-Fen Li, Juan Guo, Ping Zhang*, You-Kai Xu*. Two new limonoids from the roots of Trichilia connaroides with inhibitory activity against nitric oxide production in lipopolysaccharide-stimulated RAW 264.7 cells. Phytochemistry Letters, 2015, 14, 234-238. (First author)
(15) Kai-long Ji, Ping Zhang, Xiao-Nian Li, Juan Guo, Hua-Bin Hu, Chun-Fen Xiao, Xiang-Qun Xie, You-Kai Xu*. Cytotoxic limonoids from Trichilia americana leaves. Phytochemistry, 2015, 118, 61-67. (First author)
(16) Kai-long Ji, Ping Zhang, Hua-Bin Hu, Shuai Hua, Shang-Gao Liao*, You-Kai Xu*. Limonoids from the leaves and twigs of Walsura yunnanensis. Journal of Natural Products, 2014, 77, 764-1769. (First author)
(17) Kai-long Ji, Shang-Gao Liao, Xiao-Ling Zheng, Zhi Na, Hua-Bin Hu, Ping Zhang*, You-Kai Xu. Limonoids from the Fruits of Khaya ivorensis. Molecules, 2014, 19, 3004-3011. (First author)
Projects
Yunnan Fundamental Research Projects- General Project, 202101AT070055, CNY 100,000, 2021-2024, Project leader
Yunnan Fundamental Research Projects-Youth Project, 202101AU070148, CNY 50,000, (2021-2024), Project leader
CAS Key Laboratory of Tropical Plant Resources and Sustainable Use for Youth Development Project, 20228012802, CNY 100,000, (2022-2024), Project leader
NSFC General Project, 21772212, CNY 640,000, (2018-2021), Major participant
NSFC Youth Project, 81602991, CNY 170,000, (2017-2019), Participant
